Artificial Intelligence (AI) is now ubiquitous and facilitates a high degree of automatization in various application domains. The goal of the Bielefeld-Paderborn Joint Artificial Intelligence Institute (JAII) is to lay the foundations for human-centered AI systems that act as competent partners and feature real-world problem-solving abilities in specific domains. Instead of replacing humans, such systems will complement and empower humans by supporting them interactively in decision-making processes. The Institute follows a trans- and interdisciplinary approach, focusing on the interplay between AI and applications, as well as studying ethical, legal, and social implications of AI.